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The Role of the Keap1/Nrf2 Pathway in the Cellular Response to Methylmercury
Methylmercury (MeHg) is an environmental electrophile that covalently modifies cellular proteins with reactive thiols, resulting in the formation of protein adducts. While such protein modifications, referred to as S-mercuration, are thought to be associated with the enzyme dysfunction and cellular...
Autores principales: | Kumagai, Yoshito, Kanda, Hironori, Shinkai, Yasuhiro, Toyama, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710591/ https://www.ncbi.nlm.nih.gov/pubmed/23878621 http://dx.doi.org/10.1155/2013/848279 |
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