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Apoptosis Induced by Tanshinone IIA and Cryptotanshinone Is Mediated by Distinct JAK/STAT3/5 and SHP1/2 Signaling in Chronic Myeloid Leukemia K562 Cells

Though tanshinone IIA and cryptotanshinone possess a variety of biological effects such as anti-inflammatory, antioxidative, antimetabolic, and anticancer effects, the precise molecular targets or pathways responsible for anticancer activities of tanshinone IIA and cryptotanshinone in chronic myeloi...

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Detalles Bibliográficos
Autores principales:	Jung, Ji Hoon, Kwon, Tae-Rin, Jeong, Soo-Jin, Kim, Eun-Ok, Sohn, Eun Jung, Yun, Miyong, Kim, Sung-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710643/ https://www.ncbi.nlm.nih.gov/pubmed/23878608 http://dx.doi.org/10.1155/2013/805639

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