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Application of Design of Experiment for Floating Drug Delivery of Tapentadol Hydrochloride
The aim of the present study was to apply design of experiment (DOE) to optimize floating drug delivery of tapentadol hydrochloride. Tapentadol hydrochloride is a synthetic opioid used as a centrally acting analgesic and effective in both experimental and clinical pain. The half-life of the drug is...
Autores principales: | Jagdale, Swati C., Patil, Somnath, Kuchekar, Bhanudas S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710648/ https://www.ncbi.nlm.nih.gov/pubmed/23878616 http://dx.doi.org/10.1155/2013/625729 |
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