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Painful Boney Metastases
Boney metastasis may lead to terrible suffering from debilitating pain. The most likely malignancies that spread to bone are prostate, breast, and lung. Painful osseous metastases are typically associated with multiple episodes of breakthrough pain which may occur with activities of daily living, we...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Pain Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710936/ https://www.ncbi.nlm.nih.gov/pubmed/23861996 http://dx.doi.org/10.3344/kjp.2013.26.3.223 |
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author | Smith, Howard S. Mohsin, Intikhab |
author_facet | Smith, Howard S. Mohsin, Intikhab |
author_sort | Smith, Howard S. |
collection | PubMed |
description | Boney metastasis may lead to terrible suffering from debilitating pain. The most likely malignancies that spread to bone are prostate, breast, and lung. Painful osseous metastases are typically associated with multiple episodes of breakthrough pain which may occur with activities of daily living, weight bearing, lifting, coughing, and sneezing. Almost half of these breakthrough pain episodes are rapid in onset and short in duration and 44% of episodes are unpredictable. Treatment strategies include: analgesic approaches with "triple opioid therapy", bisphosphonates, chemotherapeutic agents, hormonal therapy, interventional and surgical approaches, steroids, radiation (external beam radiation, radiopharmaceuticals), ablative techniques (radiofrequency ablation, cryoablation), and intrathecal analgesics. |
format | Online Article Text |
id | pubmed-3710936 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | The Korean Pain Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-37109362013-07-16 Painful Boney Metastases Smith, Howard S. Mohsin, Intikhab Korean J Pain Review Article Boney metastasis may lead to terrible suffering from debilitating pain. The most likely malignancies that spread to bone are prostate, breast, and lung. Painful osseous metastases are typically associated with multiple episodes of breakthrough pain which may occur with activities of daily living, weight bearing, lifting, coughing, and sneezing. Almost half of these breakthrough pain episodes are rapid in onset and short in duration and 44% of episodes are unpredictable. Treatment strategies include: analgesic approaches with "triple opioid therapy", bisphosphonates, chemotherapeutic agents, hormonal therapy, interventional and surgical approaches, steroids, radiation (external beam radiation, radiopharmaceuticals), ablative techniques (radiofrequency ablation, cryoablation), and intrathecal analgesics. The Korean Pain Society 2013-07 2013-07-01 /pmc/articles/PMC3710936/ /pubmed/23861996 http://dx.doi.org/10.3344/kjp.2013.26.3.223 Text en Copyright © The Korean Pain Society, 2013 http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Smith, Howard S. Mohsin, Intikhab Painful Boney Metastases |
title | Painful Boney Metastases |
title_full | Painful Boney Metastases |
title_fullStr | Painful Boney Metastases |
title_full_unstemmed | Painful Boney Metastases |
title_short | Painful Boney Metastases |
title_sort | painful boney metastases |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710936/ https://www.ncbi.nlm.nih.gov/pubmed/23861996 http://dx.doi.org/10.3344/kjp.2013.26.3.223 |
work_keys_str_mv | AT smithhowards painfulboneymetastases AT mohsinintikhab painfulboneymetastases |