Src Family Kinase Inhibitor PP2 Has Different Effects on All-Trans-Retinoic Acid or Arsenic Trioxide-Induced Differentiation of an Acute Promyelocytic Leukemia Cell Line

PURPOSE: Leukemic promyelocytes have the unique ability to undergo differentiation after exposure to retinoic acid and both differentiation and apoptosis after exposure to arsenic trioxide (ATO). Recent studies have shown that inhibition of Src family kinases (SFKs) resulted in enhancement of retino...

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Detalles Bibliográficos
Autores principales: Yoon, Suk-Gu, Cheong, Hee-Jeong, Kim, Sook-Ja, Kim, Kyoung Ha, Lee, Sang-Cheol, Lee, Namsu, Park, Hee Sook, Won, Jong-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710962/
https://www.ncbi.nlm.nih.gov/pubmed/23864846
http://dx.doi.org/10.4143/crt.2013.45.2.126

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