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Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis

BACKGROUND: The development of interstitial fibrosis and tubular atrophy is a common complication after kidney transplantation and is associated with reduced long-term outcome. The hallmark of tubulointerstitial fibrosis is an increase in extracellular matrix resulting from exaggerated activation of...

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Detalles Bibliográficos
Autores principales: Zell, Stephanie, Schmitt, Roland, Witting, Sandra, Kreipe, Hans H., Hussein, Kais, Becker, Jan U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711002/
https://www.ncbi.nlm.nih.gov/pubmed/23898346
http://dx.doi.org/10.1159/000351046

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