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Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis
BACKGROUND: The development of interstitial fibrosis and tubular atrophy is a common complication after kidney transplantation and is associated with reduced long-term outcome. The hallmark of tubulointerstitial fibrosis is an increase in extracellular matrix resulting from exaggerated activation of...
Autores principales: | Zell, Stephanie, Schmitt, Roland, Witting, Sandra, Kreipe, Hans H., Hussein, Kais, Becker, Jan U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711002/ https://www.ncbi.nlm.nih.gov/pubmed/23898346 http://dx.doi.org/10.1159/000351046 |
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