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hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression
In non-small cell lung cancer cell lines, activation of β-catenin independent signaling, via Wnt7a/Frizzled9 signaling, leads to reversal of cellular transformation, reduced anchorage-independent growth and induction of epithelial differentiation. miRNA expression profiling on a human lung adenocarc...
Autores principales: | Avasarala, Sreedevi, Van Scoyk, Michelle, Wang, Jianbin, Sechler, Marybeth, Vandervest, Katherine, Brzezinski, Christine, Weekes, Colin, Edwards, Michael G., Arcaroli, John, Davis, Richard E., Bikkavilli, Rama Kamesh, Winn, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711035/ https://www.ncbi.nlm.nih.gov/pubmed/23862015 http://dx.doi.org/10.1242/bio.20134507 |
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