DNA replication-dependent binding of CTCF plays a critical role in adenovirus genome functions

The expression of adenovirus late genes is shown to require viral DNA replication, but its mechanism remains elusive. Here we found that knockdown of CTCF suppresses viral DNA replication as well as late, but not early, gene expression. Chromatin immunoprecipitation assays indicated that CTCF binds...

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Detalles Bibliográficos
Autores principales: Komatsu, Tetsuro, Sekiya, Takeshi, Nagata, Kyosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711053/
https://www.ncbi.nlm.nih.gov/pubmed/23851926
http://dx.doi.org/10.1038/srep02187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711053/
https://www.ncbi.nlm.nih.gov/pubmed/23851926
http://dx.doi.org/10.1038/srep02187

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