Thymus-derived regulatory T cells control tolerance to commensal microbiota

Peripheral mechanisms preventing autoimmunity and maintaining tolerance to commensal microbiota involve CD4(+)Foxp3(+) regulatory T cells(1,2) generated in the thymus (tTregs) or extrathymically by induction of naive CD4(+)Foxp3(−) T cells (iTregs). Prior studies suggested that the T cell receptor (...

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Detalles Bibliográficos
Autores principales: Cebula, Anna, Seweryn, Michal, Rempala, Grzegorz A., Pabla, Simarjot Singh, McIndoe, Richard A., Denning, Timothy L., Bry, Lynn, Kraj, Piotr, Kisielow, Pawel, Ignatowicz, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711137/
https://www.ncbi.nlm.nih.gov/pubmed/23624374
http://dx.doi.org/10.1038/nature12079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711137/
https://www.ncbi.nlm.nih.gov/pubmed/23624374
http://dx.doi.org/10.1038/nature12079

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