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Glycoprotein Biosynthesis in a Eukaryote Lacking the Membrane Protein Rft1
Mature dolichol-linked oligosaccharides (mDLOs) needed for eukaryotic protein N-glycosylation are synthesized by a multistep pathway in which the biosynthetic lipid intermediate Man(5)GlcNAc(2)-PP-dolichol (M5-DLO) flips from the cytoplasmic to the luminal face of the endoplasmic reticulum. The endo...
Autores principales: | Jelk, Jennifer, Gao, Ningguo, Serricchio, Mauro, Signorell, Aita, Schmidt, Remo S., Bangs, James D., Acosta-Serrano, Alvaro, Lehrman, Mark A., Bütikofer, Peter, Menon, Anant K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711325/ https://www.ncbi.nlm.nih.gov/pubmed/23720757 http://dx.doi.org/10.1074/jbc.M113.479642 |
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