FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery

Fanconi Anemia (FA) and Bloom Syndrome share overlapping phenotypes including spontaneous chromosomal abnormalities and increased cancer predisposition. The FA protein pathway comprises an upstream core complex that mediates recruitment of two central players, FANCD2 and FANCI, to sites of stalled r...

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Detalles Bibliográficos
Autores principales: Chaudhury, Indrajit, Sareen, Archana, Raghunandan, Maya, Sobeck, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711430/
https://www.ncbi.nlm.nih.gov/pubmed/23658231
http://dx.doi.org/10.1093/nar/gkt348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711430/
https://www.ncbi.nlm.nih.gov/pubmed/23658231
http://dx.doi.org/10.1093/nar/gkt348

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