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4-vinyl-substituted pyrimidine nucleosides exhibit the efficient and selective formation of interstrand cross-links with RNA and duplex DNA

The formation of interstrand cross-links in nucleic acids can have a strong impact on biological function of nucleic acids; therefore, many cross-linking agents have been developed for biological applications. Despite numerous studies, there remains a need for cross-linking agents that exhibit both...

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Detalles Bibliográficos
Autores principales:	Nishimoto, Atsushi, Jitsuzaki, Daichi, Onizuka, Kazumitsu, Taniguchi, Yosuke, Nagatsugi, Fumi, Sasaki, Shigeki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Synthetic Biology and Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711451/ https://www.ncbi.nlm.nih.gov/pubmed/23778430 http://dx.doi.org/10.1093/nar/gkt197

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