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EGFR-dependent pancreatic carcinoma cell metastasis via Rap1 activation

Tyrosine kinase receptors play an essential role in various aspects of tumor progression. In particular, epidermal growth factor receptor (EGFR) and its ligands have been implicated in the growth and dissemination of a wide array of human carcinomas. Here, we describe an EGFR-mediated signaling path...

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Detalles Bibliográficos
Autores principales: Huang, Miller, Anand, Sudarshan, Murphy, Eric A., Desgrosellier, Jay S., Stupack, Dwayne G., Shattil, Sanford J., Schlaepfer, David D., Cheresh, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711644/
https://www.ncbi.nlm.nih.gov/pubmed/21963850
http://dx.doi.org/10.1038/onc.2011.450