Cargando…
EGFR-dependent pancreatic carcinoma cell metastasis via Rap1 activation
Tyrosine kinase receptors play an essential role in various aspects of tumor progression. In particular, epidermal growth factor receptor (EGFR) and its ligands have been implicated in the growth and dissemination of a wide array of human carcinomas. Here, we describe an EGFR-mediated signaling path...
Autores principales: | Huang, Miller, Anand, Sudarshan, Murphy, Eric A., Desgrosellier, Jay S., Stupack, Dwayne G., Shattil, Sanford J., Schlaepfer, David D., Cheresh, David A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711644/ https://www.ncbi.nlm.nih.gov/pubmed/21963850 http://dx.doi.org/10.1038/onc.2011.450 |
Ejemplares similares
-
EGFR-Mediated Carcinoma Cell Metastasis Mediated by Integrin αvβ5 Depends on Activation of c-Src and Cleavage of MUC1
por: Lau, Steven K. M., et al.
Publicado: (2012) -
Integrin αvβ3/c-src “Oncogenic Unit” Promotes Anchorage-independence and Tumor Progression
por: Desgrosellier, Jay S, et al.
Publicado: (2009) -
Src-mediated coupling of focal adhesion kinase to integrin αvβ5 in vascular endothelial growth factor signaling
por: Eliceiri, Brian P., et al.
Publicado: (2002) -
Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins
por: Stupack, Dwayne G., et al.
Publicado: (2001) -
Integrin α4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN(low) Neuroblastoma
por: Young, Shanique A., et al.
Publicado: (2015)