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CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1
Carboxyl-terminal binding protein 1 (CtBP1) has been shown to suppress the transcription of several tumor suppressors in vitro. Paradoxically, a previous report showed that CtBP1 mRNA was down-regulated in melanoma. Using immunostaining, we found that a large percentage of human melanomas were posit...
Autores principales: | Deng, Hui, Liu, Jing, Deng, Yu, Han, Gangwen, Shellman, Yiqun G., Robinson, Steven, Tentler, John, Robinson, William, Norris, David A., Wang, Xiao-Jing, Zhang, Qinghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711675/ https://www.ncbi.nlm.nih.gov/pubmed/23303449 http://dx.doi.org/10.1038/jid.2012.487 |
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