Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn’s disease patients

Oral lesions may be found in patients with Crohn’s disease (CD), in a percentage up to 20%. The aim of this study was to investigate a possible relationship between Mycobacterium avium subsp. paratuberculosis (MAP) and oral lesions in CD patients. 23 oral biopsies were examined performing IS900 Nest...

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Autores principales: Molicotti, Paola, Scanu, Antonio M, Lumbau, Aurea, Cannas, Sara, Bua, Alessandra, Lugliè, Pietrina, Zanetti, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711722/
https://www.ncbi.nlm.nih.gov/pubmed/23842143
http://dx.doi.org/10.1186/1757-4749-5-18
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author Molicotti, Paola
Scanu, Antonio M
Lumbau, Aurea
Cannas, Sara
Bua, Alessandra
Lugliè, Pietrina
Zanetti, Stefania
author_facet Molicotti, Paola
Scanu, Antonio M
Lumbau, Aurea
Cannas, Sara
Bua, Alessandra
Lugliè, Pietrina
Zanetti, Stefania
author_sort Molicotti, Paola
collection PubMed
description Oral lesions may be found in patients with Crohn’s disease (CD), in a percentage up to 20%. The aim of this study was to investigate a possible relationship between Mycobacterium avium subsp. paratuberculosis (MAP) and oral lesions in CD patients. 23 oral biopsies were examined performing IS900 Nested PCR; 9 of them were positive: 8 from CD patients and 1 from a control. Our purpose is to go on with this study, amplifying the number of subjects examined and testing subjects with oral lesions related to diseases other than CD to verify the specific association between MAP and oral lesions in CD patients.
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spelling pubmed-37117222013-07-16 Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn’s disease patients Molicotti, Paola Scanu, Antonio M Lumbau, Aurea Cannas, Sara Bua, Alessandra Lugliè, Pietrina Zanetti, Stefania Gut Pathog Letter to the Editor Oral lesions may be found in patients with Crohn’s disease (CD), in a percentage up to 20%. The aim of this study was to investigate a possible relationship between Mycobacterium avium subsp. paratuberculosis (MAP) and oral lesions in CD patients. 23 oral biopsies were examined performing IS900 Nested PCR; 9 of them were positive: 8 from CD patients and 1 from a control. Our purpose is to go on with this study, amplifying the number of subjects examined and testing subjects with oral lesions related to diseases other than CD to verify the specific association between MAP and oral lesions in CD patients. BioMed Central 2013-07-10 /pmc/articles/PMC3711722/ /pubmed/23842143 http://dx.doi.org/10.1186/1757-4749-5-18 Text en Copyright © 2013 Molicotti et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Molicotti, Paola
Scanu, Antonio M
Lumbau, Aurea
Cannas, Sara
Bua, Alessandra
Lugliè, Pietrina
Zanetti, Stefania
Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn’s disease patients
title Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn’s disease patients
title_full Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn’s disease patients
title_fullStr Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn’s disease patients
title_full_unstemmed Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn’s disease patients
title_short Molecular identification of Mycobacterium avium subspecies paratuberculosis in oral biopsies of Crohn’s disease patients
title_sort molecular identification of mycobacterium avium subspecies paratuberculosis in oral biopsies of crohn’s disease patients
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711722/
https://www.ncbi.nlm.nih.gov/pubmed/23842143
http://dx.doi.org/10.1186/1757-4749-5-18
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