Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia

BACKGROUND: Elevated temperatures induce activation of the heat shock transcription factor 1 (HSF1) which in somatic cells leads to heat shock proteins synthesis and cytoprotection. However, in the male germ cells (spermatocytes) caspase-3 dependent apoptosis is induced upon HSF1 activation and sper...

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Detalles Bibliográficos
Autores principales: Kus-Liśkiewicz, Małgorzata, Polańska, Joanna, Korfanty, Joanna, Olbryt, Magdalena, Vydra, Natalia, Toma, Agnieszka, Widłak, Wiesława
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711851/
https://www.ncbi.nlm.nih.gov/pubmed/23834426
http://dx.doi.org/10.1186/1471-2164-14-456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711851/
https://www.ncbi.nlm.nih.gov/pubmed/23834426
http://dx.doi.org/10.1186/1471-2164-14-456

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