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Rupatadine Protects against Pulmonary Fibrosis by Attenuating PAF-Mediated Senescence in Rodents

A similar immune response is implicated in the pathogenesis of pulmonary fibrosis and allergic disorders. We investigated the potential therapeutic efficacy and mechanism of rupatadine, a dual antagonist of histamine and platelet-activation factor (PAF), in bleomycin- (BLM-) and silica-induced pulmo...

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Detalles Bibliográficos
Autores principales:	Lv, Xiao-xi, Wang, Xiao-xing, Li, Ke, Wang, Zi-yan, Li, Zhe, Lv, Qi, Fu, Xiao-ming, Hu, Zhuo-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711902/ https://www.ncbi.nlm.nih.gov/pubmed/23869224 http://dx.doi.org/10.1371/journal.pone.0068631

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