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Activation of Wnt/β-Catenin Signaling Increases Apoptosis in Melanoma Cells Treated with Trail
While the TRAIL pathway represents a promising therapeutic target in melanoma, resistance to TRAIL-mediated apoptosis remains a barrier to its successful adoption. Since the Wnt/β-catenin pathway has been implicated in facilitating melanoma cell apoptosis, we investigated the effect of Wnt/β-catenin...
Autores principales: | Zimmerman, Zachary F., Kulikauskas, Rima M., Bomsztyk, Karol, Moon, Randall T., Chien, Andy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711908/ https://www.ncbi.nlm.nih.gov/pubmed/23869245 http://dx.doi.org/10.1371/journal.pone.0069593 |
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