The Severity of Osteogenesis Imperfecta and Type I Collagen Pattern in Human Skin as Determined by Nonlinear Microscopy: Proof of Principle of a Diagnostic Method

BACKGROUND: The confirmatory diagnosis of Osteogenesis Imperfecta (OI) requires invasive, commonly bone biopsy, time consuming and destructive methods. This paper proposes an alternative method using a combination of two-photon excitation fluorescence (TPEF) and second-harmonic generation (SHG) micr...

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Detalles Bibliográficos
Autores principales: Adur, Javier, DSouza-Li, Lilia, Pedroni, Marcus Vinícius, Steiner, Carlos E., Pelegati, Vitor B., de Thomaz, Andre A., Carvalho, Hernandes F., Cesar, Carlos L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711916/
https://www.ncbi.nlm.nih.gov/pubmed/23869235
http://dx.doi.org/10.1371/journal.pone.0069186

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