Sticky siRNAs targeting survivin and cyclin B1 exert an antitumoral effect on melanoma subcutaneous xenografts and lung metastases

BACKGROUND: Melanoma represents one of the most aggressive and therapeutically challenging malignancies as it often gives rise to metastases and develops resistance to classical chemotherapeutic agents. Although diverse therapies have been generated, no major improvement of the patient prognosis has...

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Detalles Bibliográficos
Autores principales: Kedinger, Valerie, Meulle, Aline, Zounib, Omar, Bonnet, Marie-Elise, Gossart, Jean-Baptiste, Benoit, Elodie, Messmer, Melanie, Shankaranarayanan, Pattabhiraman, Behr, Jean-Paul, Erbacher, Patrick, Bolcato-Bellemin, Anne-Laure
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711931/
https://www.ncbi.nlm.nih.gov/pubmed/23835136
http://dx.doi.org/10.1186/1471-2407-13-338

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