Functional Redundancy of CXCR3/CXCL10 Signaling in the Recruitment of Diabetogenic Cytotoxic T Lymphocytes to Pancreatic Islets in a Virally Induced Autoimmune Diabetes Model

Cytotoxic T lymphocytes (CTLs) constitute a major effector population in pancreatic islets from patients suffering from type 1 diabetes (T1D) and thus represent attractive targets for intervention. Some studies have suggested that blocking the interaction between the chemokine CXCL10 and its recepto...

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Detalles Bibliográficos
Autores principales: Coppieters, Ken T., Amirian, Natalie, Pagni, Philippe P., Baca Jones, Carmen, Wiberg, Anna, Lasch, Stanley, Hintermann, Edith, Christen, Urs, von Herrath, Matthias G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712024/
https://www.ncbi.nlm.nih.gov/pubmed/23434930
http://dx.doi.org/10.2337/db12-1370

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