Cargando…

Meta-Immunological Profiling of Children With Type 1 Diabetes Identifies New Biomarkers to Monitor Disease Progression

Type 1 diabetes is characterized by autoimmune destruction of pancreatic β-cells in genetically susceptible individuals. Triggers of islet autoimmunity, time course, and the precise mechanisms responsible for the progressive β-cell failure are not completely understood. The recent escalation of obes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Galgani, Mario, Nugnes, Rosa, Bruzzese, Dario, Perna, Francesco, De Rosa, Veronica, Procaccini, Claudio, Mozzillo, Enza, Cilio, Corrado M., Elding Larsson, Helena, Lernmark, Åke, La Cava, Antonio, Franzese, Adriana, Matarese, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712055/ https://www.ncbi.nlm.nih.gov/pubmed/23396400 http://dx.doi.org/10.2337/db12-1273

Ejemplares similares

CD4(+) T Cell Defects in a Mulibrey Patient With Specific TRIM37 Mutations
por: Bruzzaniti, Sara, et al.
Publicado: (2020)

Perceived Difficulty with Physical Tasks, Lifestyle, and Physical Performance in Obese Children
por: Valerio, Giuliana, et al.
Publicado: (2014)

Glucose Derangements in Very Young Children With Cystic Fibrosis and Pancreatic Insufficiency
por: Mozzillo, Enza, et al.
Publicado: (2012)

Good cognitive performances in a child with Prader-Willi syndrome
por: Nugnes, Rosa, et al.
Publicado: (2013)

T1D progression is associated with loss of CD3(+)CD56(+) regulatory T cells that control CD8(+) T cell effector functions
por: Terrazzano, Giuseppe, et al.
Publicado: (2020)

Role of Adipokines Signaling in the Modulation of T Cells Function
por: Procaccini, Claudio, et al.
Publicado: (2013)

Celiac disease in type 1 diabetes mellitus
por: Camarca, Maria Erminia, et al.
Publicado: (2012)

Blood Co-Circulating Extracellular microRNAs and Immune Cell Subsets Associate with Type 1 Diabetes Severity
por: Garavelli, Silvia, et al.
Publicado: (2020)

Complete blood counts with red blood cell determinants associate with reduced beta‐cell function in seroconverted Swedish TEDDY children
por: Salami, Falastin, et al.
Publicado: (2021)

The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements
por: Procaccini, Claudio, et al.
Publicado: (2016)

The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements
por: Procaccini, Claudio, et al.
Publicado: (2016)

Decline in Titers of Anti-Idiotypic Antibodies Specific to Autoantibodies to GAD65 (GAD65Ab) Precedes Development of GAD65Ab and Type 1 Diabetes
por: Larsson, Helena Elding, et al.
Publicado: (2013)

Decreased HLA-DQ expression on peripheral blood cells in children with varying number of beta cell autoantibodies
por: Andersson Svärd, Agnes, et al.
Publicado: (2020)

Neuro-Endocrine Networks Controlling Immune System in Health and Disease
por: Procaccini, Claudio, et al.
Publicado: (2014)

Animal models of Multiple Sclerosis
por: Procaccini, Claudio, et al.
Publicado: (2015)

Long-Term Follow-Up in a Girl with Cystic Fibrosis and Diabetes Since the First Year of Life
por: Fattorusso, Valentina, et al.
Publicado: (2017)

Analysis of Corneal Deformation in Paediatric Patients Affected by Maturity Onset Diabetes of the Young Type 2
por: Lanza, Michele, et al.
Publicado: (2023)

Cystic Fibrosis-Related Diabetes (CFRD): Overview of Associated Genetic Factors
por: Iafusco, Fernanda, et al.
Publicado: (2021)

Leptin modulates autophagy in human CD4(+)CD25(−) conventional T cells
por: Cassano, Silvana, et al.
Publicado: (2014)

CD4(+) T-Cell Activation Prompts Suppressive Function by Extracellular Vesicle-Associated MicroRNAs
por: Di Silvestre, Dario, et al.
Publicado: (2021)

NGS Analysis Revealed Digenic Heterozygous GCK and HNF1A Variants in a Child with Mild Hyperglycemia: A Case Report
por: Iafusco, Fernanda, et al.
Publicado: (2021)

Precocious Pseudo-Puberty in a 7-Year-Old Girl Due to Malignant Mixed Ovarian Germ Cell Tumor
por: Improda, Nicola, et al.
Publicado: (2023)

HLA high-resolution typing by next-generation sequencing in Pandemrix-induced narcolepsy
por: Lind, Alexander, et al.
Publicado: (2019)

Diagnosis of congenital Hyperinsulinism can occur not only in infancy but also in later age: a new flow chart from a single center experience
por: Casertano, Alberto, et al.
Publicado: (2020)

Case Report: Ophthalmologic Evaluation Over a Long Follow-Up Time in a Patient With Wolfram Syndrome Type 2: Slowly Progressive Optic Neuropathy as a Possible Clinical Finding
por: Di Iorio, Valentina, et al.
Publicado: (2021)

Diabetes outbreak during COVID19 lock-down in a prediabetic patient with cystic fibrosis long treated with glargine
por: Rosanio, Francesco Maria, et al.
Publicado: (2021)

A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY
por: Lönnrot, Maria, et al.
Publicado: (2015)

Doctor-Patient Relationship in Synchronous/Real-time Video-Consultations and In-Person Visits: An Investigation of the Perceptions of Young People with Type 1 Diabetes and Their Parents During the COVID-19 Pandemic
por: Troncone, Alda, et al.
Publicado: (2022)

Constitutional chromothripsis involving the critical region of 9q21.13 microdeletion syndrome
por: Genesio, Rita, et al.
Publicado: (2015)

HLA-DQA1 and HLA-DQB1 Alleles, Conferring Susceptibility to Celiac Disease and Type 1 Diabetes, Are More Expressed Than Non-Predisposing Alleles and Are Coordinately Regulated
por: Farina, Federica, et al.
Publicado: (2019)

An Overview of Hypoglycemia in Children Including a Comprehensive Practical Diagnostic Flowchart for Clinical Use
por: Casertano, Alberto, et al.
Publicado: (2021)

Wolfram Syndrome Type 2: A Systematic Review of a Not Easily Identifiable Clinical Spectrum
por: Rosanio, Francesco Maria, et al.
Publicado: (2022)

Growth and Risk for Islet Autoimmunity and Progression to Type 1 Diabetes in Early Childhood: The Environmental Determinants of Diabetes in the Young Study
por: Elding Larsson, Helena, et al.
Publicado: (2016)

Beta cell function in participants with single or multiple islet autoantibodies at baseline in the TEDDY Family Prevention Study: TEFA
por: Martinez, Maria Månsson, et al.
Publicado: (2020)

Influence of early-life parental severe life events on the risk of type 1 diabetes in children: the DiPiS study
por: Lundgren, Markus, et al.
Publicado: (2018)

Effect of screening for type 1 diabetes on early metabolic control: the DiPiS study
por: Lundgren, Markus, et al.
Publicado: (2018)

HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children
por: Salami, Falastin, et al.
Publicado: (2022)

Metabolic Syndrome and the Immunological Affair with the Blood–Brain Barrier
por: Mauro, Claudio, et al.
Publicado: (2015)

Impaired vibrotactile sense in children and adolescents with type 1 diabetes – Signs of peripheral neuropathy
por: Ising, Erik, et al.
Publicado: (2018)

Nine residues in HLA-DQ molecules determine with susceptibility and resistance to type 1 diabetes among young children in Sweden
por: Zhao, Lue Ping, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hv5cksdf8m363omg9ag23534q2