Developmental Role for Endocannabinoid Signaling in Regulating Glucose Metabolism and Growth

Treatment of ob/ob (obese) mice with a cannabinoid receptor 1 (Cnr1) antagonist reduces food intake, suggesting a role for endocannabinoid signaling in leptin action. We further evaluated the role of endocannabinoid signaling by analyzing the phenotype of Cnr1 knockout ob/ob mice. Double mutant anim...

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Detalles Bibliográficos
Autores principales: Li, Zhiying, Schmidt, Sarah F., Friedman, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712058/
https://www.ncbi.nlm.nih.gov/pubmed/23423572
http://dx.doi.org/10.2337/db12-0901

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