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AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer

The AMP-activated protein kinase (AMPK) is a highly conserved sensor of cellular energy that appears to have arisen at an early stage during eukaryotic evolution. In 2001 it was shown to be activated by metformin, currently the major drug for treatment for type 2 diabetes. Although the known metabol...

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Detalles Bibliográficos
Autor principal: Hardie, D. Grahame
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712072/
https://www.ncbi.nlm.nih.gov/pubmed/23801715
http://dx.doi.org/10.2337/db13-0368