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Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease
Behavioural assays represent sensitive methods for detecting neuronal dysfunction in model organisms. A number of manual methods have been established for Drosophila, however these are time-consuming and generate parameter-poor phenotype descriptors. Here, we have developed an automated computer vis...
Autores principales: | Jahn, Thomas R., Kohlhoff, Kai J., Scott, Michael, Tartaglia, Gian Gaetano, Lomas, David A., Dobson, Christopher M., Vendruscolo, Michele, Crowther, Damian C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712187/ https://www.ncbi.nlm.nih.gov/pubmed/21315762 http://dx.doi.org/10.1016/j.jneumeth.2011.01.026 |
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