Intracellular shunting of O(2)(−) contributes to charge compensation and preservation of neutrophil respiratory burst in the absence of voltage-gated proton channel activity

Proton efflux via voltage-gated proton channels (Hv1) is considered to mediate the charge compensation necessary to preserve NADPH oxidase activity during the respiratory burst. Using the Hv1 inhibitor Zn(2+), we found that the PMA-induced respiratory burst of human neutrophils is inhibited when ass...

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Detalles Bibliográficos
Autores principales: Decleva, Eva, Menegazzi, Renzo, Fasolo, Alba, Defendi, Federica, Sebastianutto, Michele, Dri, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712189/
https://www.ncbi.nlm.nih.gov/pubmed/23578765
http://dx.doi.org/10.1016/j.yexcr.2013.03.031

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