Persistence of histoplasma in adrenals 7 years after antifungal therapy

Adrenal histoplasmosis is an uncommon cause for adrenal insufficiency. The duration of treatment for adrenal histoplasmosis is not clear. Existing treatment regimens advocate antifungals given for periods ranging from 6 months to 2 years. We report here a rare case who showed persistence of histopla...

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Autores principales: Kothari, Deepak, Chopra, Shweta, Bhardwaj, Minakshi, Ajmani, Ajay K., Kulshreshtha, Bindu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712391/
https://www.ncbi.nlm.nih.gov/pubmed/23869317
http://dx.doi.org/10.4103/2230-8210.111679
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author Kothari, Deepak
Chopra, Shweta
Bhardwaj, Minakshi
Ajmani, Ajay K.
Kulshreshtha, Bindu
author_facet Kothari, Deepak
Chopra, Shweta
Bhardwaj, Minakshi
Ajmani, Ajay K.
Kulshreshtha, Bindu
author_sort Kothari, Deepak
collection PubMed
description Adrenal histoplasmosis is an uncommon cause for adrenal insufficiency. The duration of treatment for adrenal histoplasmosis is not clear. Existing treatment regimens advocate antifungals given for periods ranging from 6 months to 2 years. We report here a rare case who showed persistence of histoplasma in adrenal biopsy 7 years after being initially treated with itraconazole for 9 months. This calls for a prolonged therapy with regular review of adrenal morphology and histology in these patients.
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spelling pubmed-37123912013-07-18 Persistence of histoplasma in adrenals 7 years after antifungal therapy Kothari, Deepak Chopra, Shweta Bhardwaj, Minakshi Ajmani, Ajay K. Kulshreshtha, Bindu Indian J Endocrinol Metab Case Report Adrenal histoplasmosis is an uncommon cause for adrenal insufficiency. The duration of treatment for adrenal histoplasmosis is not clear. Existing treatment regimens advocate antifungals given for periods ranging from 6 months to 2 years. We report here a rare case who showed persistence of histoplasma in adrenal biopsy 7 years after being initially treated with itraconazole for 9 months. This calls for a prolonged therapy with regular review of adrenal morphology and histology in these patients. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3712391/ /pubmed/23869317 http://dx.doi.org/10.4103/2230-8210.111679 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kothari, Deepak
Chopra, Shweta
Bhardwaj, Minakshi
Ajmani, Ajay K.
Kulshreshtha, Bindu
Persistence of histoplasma in adrenals 7 years after antifungal therapy
title Persistence of histoplasma in adrenals 7 years after antifungal therapy
title_full Persistence of histoplasma in adrenals 7 years after antifungal therapy
title_fullStr Persistence of histoplasma in adrenals 7 years after antifungal therapy
title_full_unstemmed Persistence of histoplasma in adrenals 7 years after antifungal therapy
title_short Persistence of histoplasma in adrenals 7 years after antifungal therapy
title_sort persistence of histoplasma in adrenals 7 years after antifungal therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712391/
https://www.ncbi.nlm.nih.gov/pubmed/23869317
http://dx.doi.org/10.4103/2230-8210.111679
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