Cargando…
A Screen for Morphological Complexity Identifies Regulators of Switch-like Transitions between Discrete Cell Shapes
The way in which cells adopt different morphologies is not fully understood. Cell shape could be a continuous variable or restricted to a set of discrete forms. We developed quantitative methods to describe cell shape and show that Drosophila hemocytes in culture are a heterogeneous mixture of five...
Autores principales: | Yin, Zheng, Sadok, Amine, Sailem, Heba, McCarthy, Afshan, Xia, Xiaofeng, Li, Fuhai, Garcia, Mar Arias, Evans, Louise, Barr, Alexis, Perrimon, Norbert, Marshall, Christopher J, Wong, Stephen T.C., Bakal, Chris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712499/ https://www.ncbi.nlm.nih.gov/pubmed/23748611 http://dx.doi.org/10.1038/ncb2764 |
Ejemplares similares
-
Identification of clinically predictive metagenes that encode components of a network coupling cell shape to transcription by image-omics
por: Sailem, Heba Z., et al.
Publicado: (2017) -
Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity
por: Sailem, Heba, et al.
Publicado: (2014) -
Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens
por: Yin, Zheng, et al.
Publicado: (2008) -
Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells
por: Cooper, Sam, et al.
Publicado: (2015) -
Visualizing quantitative microscopy data: History and challenges
por: Sailem, Heba Z., et al.
Publicado: (2016)