Cargando…

The Tousled-Like Kinases as Guardians of Genome Integrity

The Tousled-like kinases (TLKs) function in processes of chromatin assembly, including replication, transcription, repair, and chromosome segregation. TLKs interact specifically (and phosphorylate) with the chromatin assembly factor Asf1, a histone H3-H4 chaperone, histone H3 itself at Ser10, and al...

Descripción completa

Detalles Bibliográficos
Autor principal:	De Benedetti, Arrigo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scholarly Research Network 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712517/ https://www.ncbi.nlm.nih.gov/pubmed/23869254 http://dx.doi.org/10.5402/2012/627596

Ejemplares similares

Untousling the Role of Tousled-like Kinase 1 in DNA Damage Repair
por: Ghosh, Ishita, et al.
Publicado: (2023)

Targeting Prostate Cancer, the ‘Tousled Way’
por: Bhoir, Siddhant, et al.
Publicado: (2023)

Tousled-like kinase 1: a novel factor with multifaceted role in mCRPC progression and development of therapy resistance
por: Khalil, Md Imtiaz, et al.
Publicado: (2022)

Tousled kinase TLK1B mediates chromatin assembly in conjunction with Asf1 regardless of its kinase activity
por: De Benedetti, Arrigo
Publicado: (2010)

Molecular basis of Tousled-Like Kinase 2 activation
por: Mortuza, Gulnahar B., et al.
Publicado: (2018)

Tousled kinase TLK1B counteracts the effect of Asf1 in inhibition of histone H3–H4 tetramer formation
por: De Benedetti, Arrigo
Publicado: (2009)

DNA damage response and repair data with pharmacological modulators of Tousled
por: Timiri Shanmugam, Prakash Srinivasan, et al.
Publicado: (2016)

The Drosophila Splicing Factor PSI Is Phosphorylated by Casein Kinase II and Tousled-Like Kinase
por: Taliaferro, J. Matthew, et al.
Publicado: (2013)

The protein kinase TOUSLED facilitates RNAi in Arabidopsis
por: Uddin, Mohammad Nazim, et al.
Publicado: (2014)

Knockdown of Tousled-like kinase 1 inhibits survival of glioblastoma multiforme cells
por: Ibrahim, Kamariah, et al.
Publicado: (2020)

mars and tousled-like kinase act in parallel to ensure chromosome fidelity in Drosophila
por: Li, Hsing-Hsi, et al.
Publicado: (2009)

Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres
por: Segura-Bayona, Sandra, et al.
Publicado: (2020)

Phosphorylation-Mediated Control of Histone Chaperone ASF1 Levels by Tousled-Like Kinases
por: Pilyugin, Maxim, et al.
Publicado: (2009)

Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication
por: Klimovskaia, Ilnaz M, et al.
Publicado: (2014)

Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry
por: Simon, Bertrand, et al.
Publicado: (2022)

Tousled-like kinases stabilize replication forks and show synthetic lethality with checkpoint and PARP inhibitors
por: Lee, Sung-Bau, et al.
Publicado: (2018)

Purification, crystallization and preliminary X-ray diffraction analysis of the kinase domain of human tousled-like kinase 2
por: Garrote, Ana M., et al.
Publicado: (2014)

Comprehensive functional analysis of the tousled-like kinase 2 frequently amplified in aggressive luminal breast cancers
por: Kim, Jin-Ah, et al.
Publicado: (2016)

Histone Variants: Guardians of Genome Integrity
por: Ferrand, Juliette, et al.
Publicado: (2020)

Tousled-like kinase 1 is a negative regulator of core transcription factors in murine embryonic stem cells
por: Lee, Jina, et al.
Publicado: (2018)

The Chromosomal Passenger Complex and a Mitotic Kinesin Interact with the Tousled-Like Kinase in Trypanosomes to Regulate Mitosis and Cytokinesis
por: Li, Ziyin, et al.
Publicado: (2008)

High yield bacterial expression, purification and characterisation of bioactive Human Tousled-like Kinase 1B involved in cancer
por: Bhoir, Siddhant, et al.
Publicado: (2018)

Tousled-like kinase regulates cytokine-mediated communication between cooperating cell types during collective border cell migration
por: Xiang, Wenjuan, et al.
Publicado: (2016)

LHC-like Proteins: The Guardians of Photosynthesis
por: Levin, Guy, et al.
Publicado: (2023)

Discretionary Transduction of MMP-Sensitized Tousled in Head and Neck Cancer
por: Nair, Renjith Parameswaran, et al.
Publicado: (2019)

Tousled-Like Kinase-Dependent Phosphorylation of Rad9 Plays a Role in Cell Cycle Progression and G2/M Checkpoint Exit
por: Kelly, Ryan, et al.
Publicado: (2013)

Is DNA methylation the new guardian of the genome?
por: Hoffman, Robert M.
Publicado: (2017)

ZAR1: Guardian of plant kinases
por: Breit-McNally, Clare, et al.
Publicado: (2022)

Toll-Like Receptors in Leishmania Infections: Guardians or Promoters?
por: Faria, Marilia S., et al.
Publicado: (2012)

Guardians of the Genome: BRCA2 and Its Partners
por: Le, Hang Phuong, et al.
Publicado: (2021)

Post-Translational Modifications of the Energy Guardian AMP-Activated Protein Kinase
por: Ovens, Ashley J., et al.
Publicado: (2021)

The RUNX Family, a Novel Multifaceted Guardian of the Genome
por: Dutta, Bibek, et al.
Publicado: (2023)

Endocannabinoids as Guardians of Metastasis
por: Tegeder, Irmgard
Publicado: (2016)

On the road with WRAP53β: guardian of Cajal bodies and genome integrity
por: Henriksson, Sofia, et al.
Publicado: (2015)

The guardian
por: ATLAS Collaboration
Publicado: (2015)

Lactoferrin as a Human Genome “Guardian”—An Overall Point of View
por: Bukowska-Ośko, Iwona, et al.
Publicado: (2022)

Autophagy: Guardian of Skin Barrier
por: Kim, Hyun Jee, et al.
Publicado: (2022)

The Leicester Guardians
Publicado: (1899)

BAP1 as a guardian of genome stability: implications in human cancer
por: Kwon, Jongbum, et al.
Publicado: (2023)

p63 the guardian of human reproduction
por: Amelio, Ivano, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_o3mpk80h6j77shk586ccuhsgta