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Mesenchymal stem cells deliver synthetic microRNA mimics to glioma cells and glioma stem cells and inhibit their cell migration and self-renewal
MicroRNAs (miRNAs) have emerged as potential cancer therapeutics; however, their clinical use is hindered by lack of effective delivery mechanisms to tumor sites. Mesenchymal stem cells (MSCs) have been shown to migrate to experimental glioma and to exert anti-tumor effects by delivering cytotoxic c...
Autores principales: | Lee, Hae Kyung, Finniss, Susan, Cazacu, Simona, Bucris, Efrat, Ziv-Av, Amotz, Xiang, Cunli, Bobbitt, Kevin, Rempel, Sandra A., Hasselbach, Laura, Mikkelsen, Tom, Slavin, Shimon, Brodie, Chaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712579/ https://www.ncbi.nlm.nih.gov/pubmed/23548312 |
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