Cargando…

Nuclear magnetic resonance in conjunction with functional genomics suggests mitochondrial dysfunction in a murine model of cancer cachexia

Cancer patients commonly suffer from cachexia, a syndrome in which tumors induce metabolic changes in the host that lead to massive loss in skeletal muscle mass. Using a preclinical mouse model of cancer cachexia, we tested the hypothesis that tumor inoculation causes a reduction in ATP synthesis an...

Descripción completa

Detalles Bibliográficos
Autores principales:	CONSTANTINOU, CATERINA, FONTES DE OLIVEIRA, CIBELY CRISTINE, MINTZOPOULOS, DIONYSSIOS, BUSQUETS, SILVIA, HE, JIANXIN, KESARWANI, MEENU, MINDRINOS, MICHAEL, RAHME, LAURENCE G., ARGILÉS, JOSEP M., TZIKA, A. ARIA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712618/ https://www.ncbi.nlm.nih.gov/pubmed/21069263 http://dx.doi.org/10.3892/ijmm.2010.557

Ejemplares similares

Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model
por: Tzika, A. Aria, et al.
Publicado: (2013)

Cachexia: a problem of energetic inefficiency
por: Argilés, Josep M., et al.
Publicado: (2014)

Effects of a small, volatile bacterial molecule on Pseudomonas aeruginosa bacteria using whole cell high-resolution magic angle spinning nuclear magnetic resonance spectroscopy and genomics
por: Righi, Valeria, et al.
Publicado: (2018)

In vivo high-resolution magic angle spinning magnetic resonance spectroscopy of Drosophila melanogaster at 14.1 T shows trauma in aging and in innate immune-deficiency is linked to reduced insulin signaling
por: RIGHI, VALERIA, et al.
Publicado: (2010)

Molecular characterization and quantification using state of the art solid-state adiabatic TOBSY NMR in burn trauma
por: RIGHI, VALERIA, et al.
Publicado: (2009)

A Small Volatile Bacterial Molecule Triggers Mitochondrial Dysfunction in Murine Skeletal Muscle
por: Tzika, A. Aria, et al.
Publicado: (2013)

Bacterial-excreted small volatile molecule 2-aminoacetophenone induces oxidative stress and apoptosis in murine skeletal muscle
por: BANDYOPADHAYA, ARUNAVA, et al.
Publicado: (2016)

Diffusion tensor and volumetric magnetic resonance imaging using an MR-compatible hand-induced robotic device suggests training-induced neuroplasticity in patients with chronic stroke
por: LAZARIDOU, ASIMINA, et al.
Publicado: (2013)

High-resolution magic angle spinning magnetic resonance spectroscopy detects glycine as a biomarker in brain tumors
por: RIGHI, VALERIA, et al.
Publicado: (2010)

Theophylline is able to partially revert cachexia in tumour-bearing rats
por: Olivan, Mireia, et al.
Publicado: (2012)

Nonmuscle Tissues Contribution to Cancer Cachexia
por: Argilés, Josep M., et al.
Publicado: (2015)

Therapeutic strategies against cancer cachexia
por: Argilés, Josep M., et al.
Publicado: (2019)

fMRI as a molecular imaging procedure for the functional reorganization of motor systems in chronic stroke
por: LAZARIDOU, ASIMINA, et al.
Publicado: (2013)

In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury
por: CONSTANTINOU, CATERINA, et al.
Publicado: (2016)

Optimal management of cancer anorexia–cachexia syndrome
por: Argilés, Josep M, et al.
Publicado: (2010)

Are there any benefits of exercise training in cancer cachexia?
por: Argilés, Josep M., et al.
Publicado: (2012)

The animal cachexia score (ACASCO)
por: Betancourt, Angelica, et al.
Publicado: (2019)

Distinct Behaviour of Sorafenib in Experimental Cachexia-Inducing Tumours: The Role of STAT3
por: Toledo, Míriam, et al.
Publicado: (2014)

A Quorum Sensing Small Volatile Molecule Promotes Antibiotic Tolerance in Bacteria
por: Que, Yok-Ai, et al.
Publicado: (2013)

Functional MRI of Rehabilitation in Chronic Stroke Patients Using Novel MR-Compatible Hand Robots
por: Mintzopoulos, Dionyssios, et al.
Publicado: (2008)

The cachexia score (CASCO): a new tool for staging cachectic cancer patients
por: Argilés, Josep M., et al.
Publicado: (2011)

Pseudomonas aeruginosa Quorum Sensing Molecule Alters Skeletal Muscle Protein Homeostasis by Perturbing the Antioxidant Defense System
por: Bandyopadhaya, Arunava, et al.
Publicado: (2019)

Erratum for Bandyopadhaya et al., “Pseudomonas aeruginosa Quorum Sensing Molecule Alters Skeletal Muscle Protein Homeostasis by Perturbing the Antioxidant Defense System”
por: Bandyopadhaya, Arunava, et al.
Publicado: (2020)

Formoterol in the treatment of experimental cancer cachexia: effects on heart function
por: Toledo, Míriam, et al.
Publicado: (2014)

The Quorum Sensing Volatile Molecule 2-Amino Acetophenon Modulates Host Immune Responses in a Manner that Promotes Life with Unwanted Guests
por: Bandyopadhaya, Arunava, et al.
Publicado: (2012)

Combined approach to counteract experimental cancer cachexia: eicosapentaenoic acid and training exercise
por: Penna, Fabio, et al.
Publicado: (2011)

Effects of S‐pindolol in mouse pancreatic and lung cancer cachexia models
por: Springer, Jochen, et al.
Publicado: (2023)

Open source in cachexia?
por: Stemmler, Britta, et al.
Publicado: (2015)

Lack of Synergy Between β-Agonist Treatment and a Blockage of Sarcoplasmic Calcium Flow in a Rat Cancer Cachexia Model
por: Busquets, Silvia, et al.
Publicado: (2021)

A multifactorial anti‐cachectic approach for cancer cachexia in a rat model undergoing chemotherapy
por: Toledo, Míriam, et al.
Publicado: (2015)

Magnetization transfer contrast MRI in GFP-tagged live bacteria
por: Righi, Valeria, et al.
Publicado: (2019)

Validation of the CAchexia SCOre (CASCO). Staging Cancer Patients: The Use of miniCASCO as a Simplified Tool
por: Argilés, Josep M., et al.
Publicado: (2017)

The atypical β‐blocker S‐oxprenolol reduces cachexia and improves survival in a rat cancer cachexia model
por: Yuan, Luping, et al.
Publicado: (2022)

Identification of Anti-virulence Compounds That Disrupt Quorum-Sensing Regulated Acute and Persistent Pathogenicity
por: Starkey, Melissa, et al.
Publicado: (2014)

Inflammation in Cachexia
por: Seelaender, M., et al.
Publicado: (2015)

Effect of Cancer-Related Cachexia and Associated Changes in Nutritional Status, Inflammatory Status, and Muscle Mass on Immunotherapy Efficacy and Survival in Patients with Advanced Non-Small Cell Lung Cancer
por: Madeddu, Clelia, et al.
Publicado: (2023)

Correction: A Quorum Sensing Regulated Small Volatile Molecule Reduces Acute Virulence and Promotes Chronic Infection Phenotypes
por: Kesarwani, Meenu, et al.
Publicado: (2011)

A Quorum Sensing Regulated Small Volatile Molecule Reduces Acute Virulence and Promotes Chronic Infection Phenotypes
por: Kesarwani, Meenu, et al.
Publicado: (2011)

Displaced Myonuclei in Cancer Cachexia Suggest Altered Innervation
por: Daou, Nissrine, et al.
Publicado: (2020)

Editorial: Biological Mechanism-Based and Patient-Centered Management of Cancer-Related Symptoms and Syndromes
por: Macciò, Antonio, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6h8blamehe1mlrbu9hor5oqvf2