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Succinate Dehydrogenase B Subunit Immunohistochemical Expression Predicts Aggressiveness in Well Differentiated Neuroendocrine Tumors of the Ileum
Immunohistochemical loss of the succinate dehydrogenase subunit B (SDHB) has recently been reported as a surrogate biomarker of malignancy in sporadic and familial pheocromocytomas and paragangliomas through the activation of hypoxia pathways. However, data on the prevalence and the clinical implica...
Autores principales: | Milione, Massimo, Pusceddu, Sara, Gasparini, Patrizia, Melotti, Flavia, Maisonneuve, Patrick, Mazzaferro, Vincenzo, de Braud, Filippo G., Pelosi, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712706/ https://www.ncbi.nlm.nih.gov/pubmed/24213468 http://dx.doi.org/10.3390/cancers4030808 |
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