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Automated Quantitative Analysis of p53, Cyclin D1, Ki67 and pERK Expression in Breast Carcinoma Does Not Differ from Expert Pathologist Scoring and Correlates with Clinico-Pathological Characteristics

There is critical need for improved biomarker assessment platforms which integrate traditional pathological parameters (TNM stage, grade and ER/PR/HER2 status) with molecular profiling, to better define prognostic subgroups or systemic treatment response. One roadblock is the lack of semi-quantitati...

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Detalles Bibliográficos
Autores principales: Cass, Jamaica D., Varma, Sonal, Day, Andrew G., Sangrar, Waheed, Rajput, Ashish B., Raptis, Leda H., Squire, Jeremy, Madarnas, Yolanda, SenGupta, Sandip K., Elliott, Bruce E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712710/
https://www.ncbi.nlm.nih.gov/pubmed/24213463
http://dx.doi.org/10.3390/cancers4030725