Cargando…

RGD-Binding Integrins in Prostate Cancer: Expression Patterns and Therapeutic Prospects against Bone Metastasis

Prostate cancer is the third leading cause of male cancer deaths in the developed world. The current lack of highly specific detection methods and efficient therapeutic agents for advanced disease have been identified as problems requiring further research. The integrins play a vital role in the cro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sutherland, Mark, Gordon, Andrew, Shnyder, Steven D., Patterson, Laurence H., Sheldrake, Helen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712721/ https://www.ncbi.nlm.nih.gov/pubmed/24213501 http://dx.doi.org/10.3390/cancers4041106

Ejemplares similares

RGD-Binding Integrins in Head and Neck Cancers
por: Ahmedah, Hanadi Talal, et al.
Publicado: (2017)

Synthesis and Biological Evaluation of Cyclobutane-Based β3 Integrin Antagonists: A Novel Approach to Targeting Integrins for Cancer Therapy
por: Sutherland, Mark, et al.
Publicado: (2023)

Tuning RGD Motif and Hyaluronan Density to Study Integrin Binding
por: Zapp, Cornelia, et al.
Publicado: (2018)

Beyond RGD: virus interactions with integrins
por: Hussein, Hosni A. M., et al.
Publicado: (2015)

A Comprehensive Evaluation of the Activity and Selectivity Profile of Ligands for RGD-binding Integrins
por: Kapp, Tobias G., et al.
Publicado: (2017)

Exploring the Role of RGD-Recognizing Integrins in Cancer
por: Nieberler, Markus, et al.
Publicado: (2017)

Pseudomonas aeruginosa PilY1 Binds Integrin in an RGD- and Calcium-Dependent Manner
por: Johnson, Michael D. L., et al.
Publicado: (2011)

The effect of antagonizing RGD-binding integrin activity in papillary thyroid cancer cell lines
por: Cheng, Weiwei, et al.
Publicado: (2016)

The Adenovirus Type 3 Dodecahedron's RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding
por: Gout, E., et al.
Publicado: (2010)

Short-fibre modification facilitates adenovirus-mediated gene delivery in rheumatoid arthritis synoviocytes and synovium: role of RGD and non-RGD binding integrins
por: Toh, M-L, et al.
Publicado: (2005)

Identification of a Common Pharmacophore for Binding to MMP2 and RGD Integrin: Towards a Multitarget Approach to Inhibit Cancer Angiogenesis and Metastasis
por: Baldini, Lorenzo, et al.
Publicado: (2022)

Click Chemistry for the Synthesis of RGD-Containing Integrin Ligands
por: Colombo, Matteo, et al.
Publicado: (2010)

Neutrophil Extracellular Traps as an Adhesion Substrate for Different Tumor Cells Expressing RGD-Binding Integrins
por: Monti, Marcello, et al.
Publicado: (2018)

αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation
por: Benito-Jardón, María, et al.
Publicado: (2020)

Pharmacologic inhibition of RGD‐binding integrins ameliorates fibrosis and improves function following kidney injury
por: Basta, Jeannine, et al.
Publicado: (2020)

Can the SARS-CoV-2 Spike Protein Bind Integrins Independent of the RGD Sequence?
por: Beaudoin, Christopher A., et al.
Publicado: (2021)

Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles
por: D’Amore, Vincenzo Maria, et al.
Publicado: (2023)

Epitopes in α8β1 and other RGD-binding integrins delineate classes of integrin-blocking antibodies and major binding loops in α subunits
por: Nishimichi, Norihisa, et al.
Publicado: (2015)

Integrin‐Targeting Fluorescent Proteins: Exploration of RGD Insertion Sites
por: Sonntag, Michael H., et al.
Publicado: (2017)

SPECT/CT Imaging of High-Risk Atherosclerotic Plaques using Integrin-Binding RGD Dimer Peptides
por: Sun Yoo, Jung, et al.
Publicado: (2015)

Multivalency Increases the Binding Strength of RGD Peptidomimetic‐Paclitaxel Conjugates to Integrin α(V)β(3)
por: Raposo Moreira Dias, André, et al.
Publicado: (2017)

Correction: αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation
por: Benito-Jardón, María, et al.
Publicado: (2020)

A new perspective in sepsis treatment: could RGD-dependent integrins be novel targets?
por: Nader, Danielle, et al.
Publicado: (2020)

Dissociation Constant of Integrin-RGD Binding in Live Cells from Automated Micropipette and Label-Free Optical Data
por: Gerecsei, Tamás, et al.
Publicado: (2021)

Inhibition of the alpha-ν integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo
por: Buerkle, M A, et al.
Publicado: (2002)

Alendronate/cRGD-Decorated Ultrafine Hyaluronate Dot Targeting Bone Metastasis
por: Lee, Eunsol, et al.
Publicado: (2020)

A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins
Publicado: (1995)

Hierarchical Quatsome-RGD Nanoarchitectonic Surfaces for Enhanced Integrin-Mediated Cell Adhesion
por: Martínez-Miguel, Marc, et al.
Publicado: (2022)

LIC12254 Is a Leptospiral Protein That Interacts with Integrins via the RGD Motif
por: Cavenague, Maria F., et al.
Publicado: (2023)

Insights into the Binding of Cyclic RGD Peptidomimetics to α(5)β(1) Integrin by using Live‐Cell NMR And Computational Studies
por: Guzzetti, Ileana, et al.
Publicado: (2016)

Biological and Clinical Consequences of Integrin Binding via a Rogue RGD Motif in the SARS CoV-2 Spike Protein
por: Makowski, Lee, et al.
Publicado: (2021)

RGD-Binding Integrins Revisited: How Recently Discovered Functions and Novel Synthetic Ligands (Re-)Shape an Ever-Evolving Field
por: Ludwig, Beatrice S., et al.
Publicado: (2021)

RGD‐binding integrins and TGF‐β in SARS‐CoV‐2 infections – novel targets to treat COVID‐19 patients?
por: Carvacho, Ingrid, et al.
Publicado: (2021)

The use of thermographic imaging to evaluate therapeutic response in human tumour xenograft models
por: Hussain, Nosheen, et al.
Publicado: (2016)

A Dual Molecular Biointerface Combining RGD and KRSR Sequences Improves Osteoblastic Functions by Synergizing Integrin and Cell-Membrane Proteoglycan Binding
por: Hoyos-Nogués, Mireia, et al.
Publicado: (2019)

The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection
por: Bieri, Manuela, et al.
Publicado: (2021)

The role of integrin family in bone metabolism and tumor bone metastasis
por: Mao, Liwei, et al.
Publicado: (2023)

Intramolecular thermal stepwise [2 + 2] cycloadditions: investigation of a stereoselective synthesis of [n.2.0]-bicyclolactones
por: Throup, Adam, et al.
Publicado: (2016)

Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin α(v)β(3)
por: Chen, Haojun, et al.
Publicado: (2016)

Interface Immobilization Chemistry of cRGD-based Peptides Regulates Integrin Mediated Cell Adhesion
por: Pallarola, Diego, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2kf8oeqrv11he4pab85filgvrj