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In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography

BACKGROUND: Sarcoptes scabiei can be visualized with different imaging tools. Optical coherence tomography (OCT) may have the potential to describe the changes in skin morphology due to scabies infestation and visualize the parasite. METHODS: Five patients from the Departments of Dermatology, Augsbu...

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Autores principales: Banzhaf, Christina Alette, Themstrup, Lotte, Ring, Hans Christian, Welzel, Julia, Mogensen, Mette, Jemec, Gregor Borut Ernst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712805/
https://www.ncbi.nlm.nih.gov/pubmed/23874291
http://dx.doi.org/10.1159/000352066
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author Banzhaf, Christina Alette
Themstrup, Lotte
Ring, Hans Christian
Welzel, Julia
Mogensen, Mette
Jemec, Gregor Borut Ernst
author_facet Banzhaf, Christina Alette
Themstrup, Lotte
Ring, Hans Christian
Welzel, Julia
Mogensen, Mette
Jemec, Gregor Borut Ernst
author_sort Banzhaf, Christina Alette
collection PubMed
description BACKGROUND: Sarcoptes scabiei can be visualized with different imaging tools. Optical coherence tomography (OCT) may have the potential to describe the changes in skin morphology due to scabies infestation and visualize the parasite. METHODS: Five patients from the Departments of Dermatology, Augsburg, Germany, and Roskilde, Denmark, were OCT scanned (VivoSight(®); Michelson Diagnostics Ltd., UK). Mites were identified by epiluminescence and light microscopy to confirm the diagnosis. RESULTS: OCT identified S. scabiei mites in all patients in vivo. Mites and burrows were visualized, and some detail on burrow content was provided. CONCLUSION: OCT can visualize S. scabiei mites in vivo, suggesting that it may be used to study the biology of the mites in vivo and provide early assessment of scabicide therapy. OCT is able to visualize structures in the skin with an 8-μm resolution. Therefore, this technology could potentially allow rapid, non-invasive, in vivo diagnosis and analysis of infestations.
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spelling pubmed-37128052013-07-19 In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography Banzhaf, Christina Alette Themstrup, Lotte Ring, Hans Christian Welzel, Julia Mogensen, Mette Jemec, Gregor Borut Ernst Case Rep Dermatol Published online: June, 2013 BACKGROUND: Sarcoptes scabiei can be visualized with different imaging tools. Optical coherence tomography (OCT) may have the potential to describe the changes in skin morphology due to scabies infestation and visualize the parasite. METHODS: Five patients from the Departments of Dermatology, Augsburg, Germany, and Roskilde, Denmark, were OCT scanned (VivoSight(®); Michelson Diagnostics Ltd., UK). Mites were identified by epiluminescence and light microscopy to confirm the diagnosis. RESULTS: OCT identified S. scabiei mites in all patients in vivo. Mites and burrows were visualized, and some detail on burrow content was provided. CONCLUSION: OCT can visualize S. scabiei mites in vivo, suggesting that it may be used to study the biology of the mites in vivo and provide early assessment of scabicide therapy. OCT is able to visualize structures in the skin with an 8-μm resolution. Therefore, this technology could potentially allow rapid, non-invasive, in vivo diagnosis and analysis of infestations. S. Karger AG 2013-06-01 /pmc/articles/PMC3712805/ /pubmed/23874291 http://dx.doi.org/10.1159/000352066 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: June, 2013
Banzhaf, Christina Alette
Themstrup, Lotte
Ring, Hans Christian
Welzel, Julia
Mogensen, Mette
Jemec, Gregor Borut Ernst
In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography
title In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography
title_full In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography
title_fullStr In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography
title_full_unstemmed In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography
title_short In vivo Imaging of Sarcoptes scabiei Infestation Using Optical Coherence Tomography
title_sort in vivo imaging of sarcoptes scabiei infestation using optical coherence tomography
topic Published online: June, 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712805/
https://www.ncbi.nlm.nih.gov/pubmed/23874291
http://dx.doi.org/10.1159/000352066
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