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Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases

Animal studies generate valuable hypotheses that lead to the conduct of preventive or therapeutic clinical trials. We assessed whether there is evidence for excess statistical significance in results of animal studies on neurological disorders, suggesting biases. We used data from meta-analyses of i...

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Detalles Bibliográficos
Autores principales:	Tsilidis, Konstantinos K., Panagiotou, Orestis A., Sena, Emily S., Aretouli, Eleni, Evangelou, Evangelos, Howells, David W., Salman, Rustam Al-Shahi, Macleod, Malcolm R., Ioannidis, John P. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712913/ https://www.ncbi.nlm.nih.gov/pubmed/23874156 http://dx.doi.org/10.1371/journal.pbio.1001609

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