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Corruption of the Intra-Gene DNA Methylation Architecture Is a Hallmark of Cancer
Epigenetic processes - including DNA methylation - are increasingly seen as having a fundamental role in chronic diseases like cancer. It is well known that methylation levels at particular genes or loci differ between normal and diseased tissue. Here we investigate whether the intra-gene methylatio...
Autores principales: | Bartlett, Thomas E., Zaikin, Alexey, Olhede, Sofia C., West, James, Teschendorff, Andrew E., Widschwendter, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712966/ https://www.ncbi.nlm.nih.gov/pubmed/23874574 http://dx.doi.org/10.1371/journal.pone.0068285 |
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