Cargando…

Functional Coding Variants in SLC6A15, a Possible Risk Gene for Major Depression

SLC6A15 is a neuron-specific neutral amino acid transporter that belongs to the solute carrier 6 gene family. This gene family is responsible for presynaptic re-uptake of the majority of neurotransmitters. Convergent data from human studies, animal models and pharmacological investigations suggest a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quast, Carina, Cuboni, Serena, Bader, Daniel, Altmann, André, Weber, Peter, Arloth, Janine, Röh, Simone, Brückl, Tanja, Ising, Marcus, Kopczak, Anna, Erhardt, Angelika, Hausch, Felix, Lucae, Susanne, Binder, Elisabeth B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712998/ https://www.ncbi.nlm.nih.gov/pubmed/23874702 http://dx.doi.org/10.1371/journal.pone.0068645

Ejemplares similares

Effects of stressful life-events on DNA methylation in panic disorder and major depressive disorder
por: Czamara, Darina, et al.
Publicado: (2022)

Re-Annotator: Annotation Pipeline for Microarray Probe Sequences
por: Arloth, Janine, et al.
Publicado: (2015)

Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
por: Zannas, Anthony S., et al.
Publicado: (2015)

Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling
por: Zannas, Anthony S., et al.
Publicado: (2018)

The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders
por: Thoeringer, C. K., et al.
Publicado: (2008)

FKBP5 Gene Expression Predicts Antidepressant Treatment Outcome in Depression
por: Ising, Marcus, et al.
Publicado: (2019)

“DNA Methylation signatures in panic disorder”
por: Iurato, Stella, et al.
Publicado: (2017)

Effects of Pharmacokinetic Gene Variation on Therapeutic Drug Levels and Antidepressant Treatment Response
por: Scherf-Clavel, Maike, et al.
Publicado: (2022)

Recurrent suicide attempts affect normalization of HPA axis dysregulation after recovery from major depression
por: Hennings, Johannes M., et al.
Publicado: (2022)

The biological classification of mental disorders (BeCOME) study: a protocol for an observational deep-phenotyping study for the identification of biological subtypes
por: Brückl, Tanja M., et al.
Publicado: (2020)

Predicting treatment outcome in depression: an introduction into current concepts and challenges
por: Rost, Nicolas, et al.
Publicado: (2022)

Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation
por: Moore, Sarah R., et al.
Publicado: (2021)

Possible Associations of NTRK2 Polymorphisms with Antidepressant Treatment Outcome: Findings from an Extended Tag SNP Approach
por: Hennings, Johannes M., et al.
Publicado: (2013)

vipR: variant identification in pooled DNA using R
por: Altmann, Andre, et al.
Publicado: (2011)

FKBP5 Genotype-Dependent DNA Methylation and mRNA Regulation After Psychosocial Stress in Remitted Depression and Healthy Controls
por: Höhne, Nina, et al.
Publicado: (2015)

Stress dynamically regulates co-expression networks of glucocorticoid receptor-dependent MDD and SCZ risk genes
por: Zimmermann, Christoph A., et al.
Publicado: (2019)

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders
por: Arloth, Janine, et al.
Publicado: (2015)

Creating sparser prediction models of treatment outcome in depression: a proof-of-concept study using simultaneous feature selection and hyperparameter tuning
por: Rost, Nicolas, et al.
Publicado: (2022)

Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus
por: Wiechmann, Tobias, et al.
Publicado: (2019)

RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response
por: Hennings, J M, et al.
Publicado: (2015)

Oxytocin and cortisol concentrations in adults with and without autism spectrum disorder in response to physical exercise
por: Albantakis, L., et al.
Publicado: (2021)

Proteomic Differences in Blood Plasma Associated with Antidepressant Treatment Response
por: Turck, Christoph W., et al.
Publicado: (2017)

Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores
por: Kirmeier, Thomas, et al.
Publicado: (2016)

Plasma fibrinogen: now also an antidepressant response marker?
por: Martins-de-Souza, D, et al.
Publicado: (2014)

Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk
por: Zannas, Anthony S., et al.
Publicado: (2019)

Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model
por: Emeny, Rebecca T, et al.
Publicado: (2018)

Versatile knowledge guided network inference method for prioritizing key regulatory factors in multi-omics data
por: Ogris, Christoph, et al.
Publicado: (2021)

Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study
por: Kappelmann, Nils, et al.
Publicado: (2020)

Stress-induced brain responses are associated with BMI in women
por: Kühnel, Anne, et al.
Publicado: (2023)

Citalopram-induced pathways regulation and tentative treatment-outcome-predicting biomarkers in lymphoblastoid cell lines from depression patients
por: Barakat, Abdul Karim, et al.
Publicado: (2020)

Uptake Transporters of the SLC21, SLC22A, and SLC15A Families in Anticancer Therapy—Modulators of Cellular Entry or Pharmacokinetics?
por: Brecht, Karin, et al.
Publicado: (2020)

Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models
por: Paul, Riya, et al.
Publicado: (2019)

The Genetic Variability of Members of the SLC38 Family of Amino Acid Transporters (SLC38A3, SLC38A7 and SLC38A9) Affects Susceptibility to Type 2 Diabetes and Vascular Complications
por: Crocco, Paolina, et al.
Publicado: (2022)

Transdiagnostic evaluation of epigenetic age acceleration and burden of psychiatric disorders
por: Yusupov, Natan, et al.
Publicado: (2023)

DiffBrainNet: Differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regions
por: Gerstner, Nathalie, et al.
Publicado: (2022)

SLC-2000: a luminosity upgrade for the SLC
por: Breidenbach, M, et al.
Publicado: (1996)

Proliferation rates and gene expression profiles in human lymphoblastoid cell lines from patients with depression characterized in response to antidepressant drug therapy
por: Breitfeld, J, et al.
Publicado: (2016)

SLC7A11 as a Gateway of Metabolic Perturbation and Ferroptosis Vulnerability in Cancer
por: Lee, Jaewang, et al.
Publicado: (2022)

DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning
por: Arloth, Janine, et al.
Publicado: (2020)

Handbook of Sports and Lottery Markets
por: Hausch, Donald
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_b9e5dj7tolhucc9ov2qm3ec6h9