Cargando…
Ribosomal Proteins RPL37, RPS15 and RPS20 Regulate the Mdm2-p53-MdmX Network
Changes to the nucleolus, the site of ribosome production, have long been linked to cancer, and mutations in several ribosomal proteins (RPs) have been associated with an increased risk for cancer in human diseases. Relevantly, a number of RPs have been shown to bind to MDM2 and inhibit MDM2 E3 liga...
Autores principales: | Daftuar, Lilyn, Zhu, Yan, Jacq, Xavier, Prives, Carol |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713000/ https://www.ncbi.nlm.nih.gov/pubmed/23874713 http://dx.doi.org/10.1371/journal.pone.0068667 |
Ejemplares similares
-
Cisplatin causes cell death via TAB1 regulation of p53/MDM2/MDMX circuitry
por: Zhu, Yan, et al.
Publicado: (2013) -
RPL15 promotes hepatocellular carcinoma progression via regulation of RPs-MDM2-p53 signaling pathway
por: Shi, Rui, et al.
Publicado: (2022) -
Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells
por: Mrkvová, Zuzana, et al.
Publicado: (2019) -
The roles and regulation of MDM2 and MDMX: it is not just about p53
por: Klein, Alyssa M., et al.
Publicado: (2021) -
Regulation of p53: a collaboration between Mdm2 and MdmX
por: Pei, Dongsheng, et al.
Publicado: (2012)