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Prediction of Cross-Recognition of Peptide-HLA A2 by Melan-A-Specific Cytotoxic T Lymphocytes Using Three-Dimensional Quantitative Structure-Activity Relationships
The cross-recognition of peptides by cytotoxic T lymphocytes is a key element in immunology and in particular in peptide based immunotherapy. Here we develop three-dimensional (3D) quantitative structure-activity relationships (QSARs) to predict cross-recognition by Melan-A-specific cytotoxic T lymp...
Autores principales: | Fagerberg, Theres, Zoete, Vincent, Viatte, Sebastien, Baumgaertner, Petra, Alves, Pedro M., Romero, Pedro, Speiser, Daniel E., Michielin, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713012/ https://www.ncbi.nlm.nih.gov/pubmed/23874382 http://dx.doi.org/10.1371/journal.pone.0065590 |
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