Decreased FANCJ caused by 5FU contributes to the increased sensitivity to oxaliplatin in gastric cancer cells

BACKGROUND: Oxaliplatin is effective against many types of cancer, and the combination of 5-fluorouracil (5FU) and oxaliplatin is synergistically effective against gastric cancer, as well as colon cancer. The FANCJ protein is one of the Fanconi anemia (FA) gene products, and its interaction with the...

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Detalles Bibliográficos
Autores principales: Mori, Ryutaro, Yoshida, Kazuhiro, Tanahashi, Toshiyuki, Yawata, Kazunori, Kato, Junko, Okumura, Naoki, Tsutani, Yasuhiro, Okada, Morihito, Oue, Naohide, Yasui, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713262/
https://www.ncbi.nlm.nih.gov/pubmed/22968820
http://dx.doi.org/10.1007/s10120-012-0191-0

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