A Rare Neurological Complication of Ranolazine

Myoclonus is not a known side effect of ranolazine. We report a case of myoclonus in a 72-year-old female who underwent cardiac catheterization for angina and was started on ranolazine after the procedure. Two days after ranolazine therapy on 1000 mg per day in divided doses, myoclonus developed, wh...

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Detalles Bibliográficos
Autores principales: Porhomayon, Jahan, Zadeii, Gino, Yarahmadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713362/
https://www.ncbi.nlm.nih.gov/pubmed/23936696
http://dx.doi.org/10.1155/2013/451206
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author Porhomayon, Jahan
Zadeii, Gino
Yarahmadi, Alireza
author_facet Porhomayon, Jahan
Zadeii, Gino
Yarahmadi, Alireza
author_sort Porhomayon, Jahan
collection PubMed
description Myoclonus is not a known side effect of ranolazine. We report a case of myoclonus in a 72-year-old female who underwent cardiac catheterization for angina and was started on ranolazine after the procedure. Two days after ranolazine therapy on 1000 mg per day in divided doses, myoclonus developed, which severely impaired her normal activity. Her symptoms resolved 2 days after discontinuation of ranolazine. Ranolazine was resumed after discharge from hospital with recurrent myoclonus after two days of therapy. The causal relationship between ranolazine and myoclonus was suggested by cessation of myoclonus after ranolazine was discontinued.
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spelling pubmed-37133622013-08-09 A Rare Neurological Complication of Ranolazine Porhomayon, Jahan Zadeii, Gino Yarahmadi, Alireza Case Rep Neurol Med Case Report Myoclonus is not a known side effect of ranolazine. We report a case of myoclonus in a 72-year-old female who underwent cardiac catheterization for angina and was started on ranolazine after the procedure. Two days after ranolazine therapy on 1000 mg per day in divided doses, myoclonus developed, which severely impaired her normal activity. Her symptoms resolved 2 days after discontinuation of ranolazine. Ranolazine was resumed after discharge from hospital with recurrent myoclonus after two days of therapy. The causal relationship between ranolazine and myoclonus was suggested by cessation of myoclonus after ranolazine was discontinued. Hindawi Publishing Corporation 2013 2013-07-01 /pmc/articles/PMC3713362/ /pubmed/23936696 http://dx.doi.org/10.1155/2013/451206 Text en Copyright © 2013 Jahan Porhomayon et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Porhomayon, Jahan
Zadeii, Gino
Yarahmadi, Alireza
A Rare Neurological Complication of Ranolazine
title A Rare Neurological Complication of Ranolazine
title_full A Rare Neurological Complication of Ranolazine
title_fullStr A Rare Neurological Complication of Ranolazine
title_full_unstemmed A Rare Neurological Complication of Ranolazine
title_short A Rare Neurological Complication of Ranolazine
title_sort rare neurological complication of ranolazine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713362/
https://www.ncbi.nlm.nih.gov/pubmed/23936696
http://dx.doi.org/10.1155/2013/451206
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