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Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region
Introduction. This study aims to assess the factors associated with 25-hydroxy vitamin D (25(OH)D) levels in pregnant women and their newborns in a sunny region. Materials and Methods. This cross-sectional study was conducted in 2012 in Isfahan, Iran. It comprised 100 nulliparous singleton pregnant...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713371/ https://www.ncbi.nlm.nih.gov/pubmed/23935619 http://dx.doi.org/10.1155/2013/460970 |
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author | Kelishadi, Roya Sharifi-Ghazvini, Faezeh Poursafa, Parinaz Mehrabian, Ferdous Farajian, Sanam Yousefy, Hosseinali Movahedian, Mahsa Sharifi-Ghazvini, Sanaz |
author_facet | Kelishadi, Roya Sharifi-Ghazvini, Faezeh Poursafa, Parinaz Mehrabian, Ferdous Farajian, Sanam Yousefy, Hosseinali Movahedian, Mahsa Sharifi-Ghazvini, Sanaz |
author_sort | Kelishadi, Roya |
collection | PubMed |
description | Introduction. This study aims to assess the factors associated with 25-hydroxy vitamin D (25(OH)D) levels in pregnant women and their newborns in a sunny region. Materials and Methods. This cross-sectional study was conducted in 2012 in Isfahan, Iran. It comprised 100 nulliparous singleton pregnant women, selected by random cluster sampling. Laboratory tests were assessed before delivery in mothers and after delivery in their infants' umbilical cord blood. The P for trend of variables was assessed across the air quality index (AQI) quartiles. The associations of AQI and 25(OH)D were assessed by multiple linear regression after adjustment for age, body mass index, and dietary intake. Results. Sera of 98 mothers and an equal number of newborns were analyzed. The median (interquartile range, IQR) of serum 25(OH)D of mothers and neonates was 15.1(12.6, 18.2) ng/mL in mothers and 15.7(12.0, 18.1) ng/mL in neonates, respectively. AQI had an inverse association with serum 25(OH)D (Beta = −0.58, P = 0.04). The corresponding figure was also inverse and significant for newborns (Beta (SE)= −0.51(0.04), P = 0.01). Conclusion. The independent inverse association of 25(OH)D with air quality can explain the high prevalence of hypovitaminosis D in pregnant women living in this sunny region. |
format | Online Article Text |
id | pubmed-3713371 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37133712013-08-09 Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region Kelishadi, Roya Sharifi-Ghazvini, Faezeh Poursafa, Parinaz Mehrabian, Ferdous Farajian, Sanam Yousefy, Hosseinali Movahedian, Mahsa Sharifi-Ghazvini, Sanaz Int J Endocrinol Clinical Study Introduction. This study aims to assess the factors associated with 25-hydroxy vitamin D (25(OH)D) levels in pregnant women and their newborns in a sunny region. Materials and Methods. This cross-sectional study was conducted in 2012 in Isfahan, Iran. It comprised 100 nulliparous singleton pregnant women, selected by random cluster sampling. Laboratory tests were assessed before delivery in mothers and after delivery in their infants' umbilical cord blood. The P for trend of variables was assessed across the air quality index (AQI) quartiles. The associations of AQI and 25(OH)D were assessed by multiple linear regression after adjustment for age, body mass index, and dietary intake. Results. Sera of 98 mothers and an equal number of newborns were analyzed. The median (interquartile range, IQR) of serum 25(OH)D of mothers and neonates was 15.1(12.6, 18.2) ng/mL in mothers and 15.7(12.0, 18.1) ng/mL in neonates, respectively. AQI had an inverse association with serum 25(OH)D (Beta = −0.58, P = 0.04). The corresponding figure was also inverse and significant for newborns (Beta (SE)= −0.51(0.04), P = 0.01). Conclusion. The independent inverse association of 25(OH)D with air quality can explain the high prevalence of hypovitaminosis D in pregnant women living in this sunny region. Hindawi Publishing Corporation 2013 2013-07-01 /pmc/articles/PMC3713371/ /pubmed/23935619 http://dx.doi.org/10.1155/2013/460970 Text en Copyright © 2013 Roya Kelishadi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Kelishadi, Roya Sharifi-Ghazvini, Faezeh Poursafa, Parinaz Mehrabian, Ferdous Farajian, Sanam Yousefy, Hosseinali Movahedian, Mahsa Sharifi-Ghazvini, Sanaz Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region |
title | Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region |
title_full | Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region |
title_fullStr | Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region |
title_full_unstemmed | Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region |
title_short | Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region |
title_sort | determinants of hypovitaminosis d in pregnant women and their newborns in a sunny region |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713371/ https://www.ncbi.nlm.nih.gov/pubmed/23935619 http://dx.doi.org/10.1155/2013/460970 |
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