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Total Body Irradiation with Step Translation and Dynamic Field Matching
The purpose of this study is to develop a total body irradiation technique that does not require additional devices or sophisticated processes to overcome the space limitation of a small treatment room. The technique aims to deliver a uniform dose to the entire body while keeping the lung dose withi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713376/ https://www.ncbi.nlm.nih.gov/pubmed/23956971 http://dx.doi.org/10.1155/2013/216034 |
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author | Chen, Ho-Hsing Wu, Jay Chuang, Keh-Shih Lin, Jia-Fu Lee, Jia-Cheng Lin, Jin-Ching |
author_facet | Chen, Ho-Hsing Wu, Jay Chuang, Keh-Shih Lin, Jia-Fu Lee, Jia-Cheng Lin, Jin-Ching |
author_sort | Chen, Ho-Hsing |
collection | PubMed |
description | The purpose of this study is to develop a total body irradiation technique that does not require additional devices or sophisticated processes to overcome the space limitation of a small treatment room. The technique aims to deliver a uniform dose to the entire body while keeping the lung dose within the tolerance level. The technique treats the patient lying on the floor anteriorly and posteriorly. For each AP/PA treatment, two complementary fields with dynamic field edges are matched over an overlapped region defined by the marks on the body surface. A compensator, a spoiler, and lung shielding blocks were used during the treatment. Moreover, electron beams were used to further boost the chest wall around the lungs. The technique was validated in a RANDO phantom using GAFCHROMIC films. Dose ratios at different body sites along the midline ranged from 0.945 to 1.076. The dose variation in the AP direction ranged from 96.0% to 104.6%. The dose distribution in the overlapped region ranged from 98.5% to 102.8%. Lateral dose profiles at abdomen and head revealed 109.8% and 111.7% high doses, respectively, at the body edges. The results confirmed that the technique is capable of delivering a uniform dose distribution to the midline of the body in a small treatment room while keeping the lung dose within the tolerance level. |
format | Online Article Text |
id | pubmed-3713376 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37133762013-08-16 Total Body Irradiation with Step Translation and Dynamic Field Matching Chen, Ho-Hsing Wu, Jay Chuang, Keh-Shih Lin, Jia-Fu Lee, Jia-Cheng Lin, Jin-Ching Biomed Res Int Research Article The purpose of this study is to develop a total body irradiation technique that does not require additional devices or sophisticated processes to overcome the space limitation of a small treatment room. The technique aims to deliver a uniform dose to the entire body while keeping the lung dose within the tolerance level. The technique treats the patient lying on the floor anteriorly and posteriorly. For each AP/PA treatment, two complementary fields with dynamic field edges are matched over an overlapped region defined by the marks on the body surface. A compensator, a spoiler, and lung shielding blocks were used during the treatment. Moreover, electron beams were used to further boost the chest wall around the lungs. The technique was validated in a RANDO phantom using GAFCHROMIC films. Dose ratios at different body sites along the midline ranged from 0.945 to 1.076. The dose variation in the AP direction ranged from 96.0% to 104.6%. The dose distribution in the overlapped region ranged from 98.5% to 102.8%. Lateral dose profiles at abdomen and head revealed 109.8% and 111.7% high doses, respectively, at the body edges. The results confirmed that the technique is capable of delivering a uniform dose distribution to the midline of the body in a small treatment room while keeping the lung dose within the tolerance level. Hindawi Publishing Corporation 2013 2013-07-01 /pmc/articles/PMC3713376/ /pubmed/23956971 http://dx.doi.org/10.1155/2013/216034 Text en Copyright © 2013 Ho-Hsing Chen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Chen, Ho-Hsing Wu, Jay Chuang, Keh-Shih Lin, Jia-Fu Lee, Jia-Cheng Lin, Jin-Ching Total Body Irradiation with Step Translation and Dynamic Field Matching |
title | Total Body Irradiation with Step Translation and Dynamic Field Matching |
title_full | Total Body Irradiation with Step Translation and Dynamic Field Matching |
title_fullStr | Total Body Irradiation with Step Translation and Dynamic Field Matching |
title_full_unstemmed | Total Body Irradiation with Step Translation and Dynamic Field Matching |
title_short | Total Body Irradiation with Step Translation and Dynamic Field Matching |
title_sort | total body irradiation with step translation and dynamic field matching |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713376/ https://www.ncbi.nlm.nih.gov/pubmed/23956971 http://dx.doi.org/10.1155/2013/216034 |
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