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Total Body Irradiation with Step Translation and Dynamic Field Matching

The purpose of this study is to develop a total body irradiation technique that does not require additional devices or sophisticated processes to overcome the space limitation of a small treatment room. The technique aims to deliver a uniform dose to the entire body while keeping the lung dose withi...

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Autores principales: Chen, Ho-Hsing, Wu, Jay, Chuang, Keh-Shih, Lin, Jia-Fu, Lee, Jia-Cheng, Lin, Jin-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713376/
https://www.ncbi.nlm.nih.gov/pubmed/23956971
http://dx.doi.org/10.1155/2013/216034
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author Chen, Ho-Hsing
Wu, Jay
Chuang, Keh-Shih
Lin, Jia-Fu
Lee, Jia-Cheng
Lin, Jin-Ching
author_facet Chen, Ho-Hsing
Wu, Jay
Chuang, Keh-Shih
Lin, Jia-Fu
Lee, Jia-Cheng
Lin, Jin-Ching
author_sort Chen, Ho-Hsing
collection PubMed
description The purpose of this study is to develop a total body irradiation technique that does not require additional devices or sophisticated processes to overcome the space limitation of a small treatment room. The technique aims to deliver a uniform dose to the entire body while keeping the lung dose within the tolerance level. The technique treats the patient lying on the floor anteriorly and posteriorly. For each AP/PA treatment, two complementary fields with dynamic field edges are matched over an overlapped region defined by the marks on the body surface. A compensator, a spoiler, and lung shielding blocks were used during the treatment. Moreover, electron beams were used to further boost the chest wall around the lungs. The technique was validated in a RANDO phantom using GAFCHROMIC films. Dose ratios at different body sites along the midline ranged from 0.945 to 1.076. The dose variation in the AP direction ranged from 96.0% to 104.6%. The dose distribution in the overlapped region ranged from 98.5% to 102.8%. Lateral dose profiles at abdomen and head revealed 109.8% and 111.7% high doses, respectively, at the body edges. The results confirmed that the technique is capable of delivering a uniform dose distribution to the midline of the body in a small treatment room while keeping the lung dose within the tolerance level.
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spelling pubmed-37133762013-08-16 Total Body Irradiation with Step Translation and Dynamic Field Matching Chen, Ho-Hsing Wu, Jay Chuang, Keh-Shih Lin, Jia-Fu Lee, Jia-Cheng Lin, Jin-Ching Biomed Res Int Research Article The purpose of this study is to develop a total body irradiation technique that does not require additional devices or sophisticated processes to overcome the space limitation of a small treatment room. The technique aims to deliver a uniform dose to the entire body while keeping the lung dose within the tolerance level. The technique treats the patient lying on the floor anteriorly and posteriorly. For each AP/PA treatment, two complementary fields with dynamic field edges are matched over an overlapped region defined by the marks on the body surface. A compensator, a spoiler, and lung shielding blocks were used during the treatment. Moreover, electron beams were used to further boost the chest wall around the lungs. The technique was validated in a RANDO phantom using GAFCHROMIC films. Dose ratios at different body sites along the midline ranged from 0.945 to 1.076. The dose variation in the AP direction ranged from 96.0% to 104.6%. The dose distribution in the overlapped region ranged from 98.5% to 102.8%. Lateral dose profiles at abdomen and head revealed 109.8% and 111.7% high doses, respectively, at the body edges. The results confirmed that the technique is capable of delivering a uniform dose distribution to the midline of the body in a small treatment room while keeping the lung dose within the tolerance level. Hindawi Publishing Corporation 2013 2013-07-01 /pmc/articles/PMC3713376/ /pubmed/23956971 http://dx.doi.org/10.1155/2013/216034 Text en Copyright © 2013 Ho-Hsing Chen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chen, Ho-Hsing
Wu, Jay
Chuang, Keh-Shih
Lin, Jia-Fu
Lee, Jia-Cheng
Lin, Jin-Ching
Total Body Irradiation with Step Translation and Dynamic Field Matching
title Total Body Irradiation with Step Translation and Dynamic Field Matching
title_full Total Body Irradiation with Step Translation and Dynamic Field Matching
title_fullStr Total Body Irradiation with Step Translation and Dynamic Field Matching
title_full_unstemmed Total Body Irradiation with Step Translation and Dynamic Field Matching
title_short Total Body Irradiation with Step Translation and Dynamic Field Matching
title_sort total body irradiation with step translation and dynamic field matching
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713376/
https://www.ncbi.nlm.nih.gov/pubmed/23956971
http://dx.doi.org/10.1155/2013/216034
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