Lifting the veil on amyloid drug design

High resolution structures and computational methods have been used to identify compounds that prevent amyloid fibrils associated with Alzheimer’s disease from dissociating into toxic species.

Detalles Bibliográficos
Autores principales: Tiller, Kathryn E, Tessier, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713451/
https://www.ncbi.nlm.nih.gov/pubmed/23878728
http://dx.doi.org/10.7554/eLife.01089
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author Tiller, Kathryn E
Tessier, Peter M
author_facet Tiller, Kathryn E
Tessier, Peter M
author_sort Tiller, Kathryn E
collection PubMed
description High resolution structures and computational methods have been used to identify compounds that prevent amyloid fibrils associated with Alzheimer’s disease from dissociating into toxic species.
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spelling pubmed-37134512013-07-22 Lifting the veil on amyloid drug design Tiller, Kathryn E Tessier, Peter M eLife Biophysics and Structural Biology High resolution structures and computational methods have been used to identify compounds that prevent amyloid fibrils associated with Alzheimer’s disease from dissociating into toxic species. eLife Sciences Publications, Ltd 2013-07-16 /pmc/articles/PMC3713451/ /pubmed/23878728 http://dx.doi.org/10.7554/eLife.01089 Text en Copyright © 2013, Tiller and Tessier http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Biophysics and Structural Biology
Tiller, Kathryn E
Tessier, Peter M
Lifting the veil on amyloid drug design
title Lifting the veil on amyloid drug design
title_full Lifting the veil on amyloid drug design
title_fullStr Lifting the veil on amyloid drug design
title_full_unstemmed Lifting the veil on amyloid drug design
title_short Lifting the veil on amyloid drug design
title_sort lifting the veil on amyloid drug design
topic Biophysics and Structural Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713451/
https://www.ncbi.nlm.nih.gov/pubmed/23878728
http://dx.doi.org/10.7554/eLife.01089
work_keys_str_mv AT tillerkathryne liftingtheveilonamyloiddrugdesign
AT tessierpeterm liftingtheveilonamyloiddrugdesign

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