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A STATement on Vemurafenib-Resistant Melanoma
Despite recent advancements in the treatment of late-stage mutant BRAF (V600E/K) melanomas, a major hurdle continues to be acquired resistance to BRAF inhibitors such as Vemurafenib. The mechanisms for resistance have proven to be heterogeneous, emphasizing the need to utilize broad therapeutic appr...
Autores principales: | Hartsough, Edward J., Aplin, Andrew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713534/ https://www.ncbi.nlm.nih.gov/pubmed/23856932 http://dx.doi.org/10.1038/jid.2013.136 |
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