Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis

Background. Aim was to elucidate the role of toll-like receptor 9 (TLR9) in cardiac inflammation and septic heart failure in a murine model of polymicrobial sepsis. Methods. Sepsis was induced via colon ascendens stent peritonitis (CASP) in C57BL/6 wild-type (WT) and TLR9-deficient (TLR9-D) mice. Ba...

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Detalles Bibliográficos
Autores principales: Lohner, Ralph, Schwederski, Markus, Narath, Carolin, Klein, Johanna, Duerr, Georg D., Torno, Alexandra, Knuefermann, Pascal, Hoeft, Andreas, Baumgarten, Georg, Meyer, Rainer, Boehm, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713595/
https://www.ncbi.nlm.nih.gov/pubmed/23935245
http://dx.doi.org/10.1155/2013/261049

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