BSE-associated Prion-Amyloid Cardiomyopathy in Primates

Prion amyloidosis occurred in the heart of 1 of 3 macaques intraperitoneally inoculated with bovine spongiform encephalopathy prions. This macaque had a remarkably long duration of disease and signs of cardiac distress. Variant Creutzfeldt-Jakob disease, caused by transmission of bovine spongiform e...

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Detalles Bibliográficos
Autores principales: Krasemann, Susanne, Mearini, Giulia, Krämer, Elisabeth, Wagenführ, Katja, Schulz-Schaeffer, Walter, Neumann, Melanie, Bodemer, Walter, Kaup, Franz-Josef, Beekes, Michael, Carrier, Lucie, Aguzzi, Adriano, Glatzel, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713817/
https://www.ncbi.nlm.nih.gov/pubmed/23735198
http://dx.doi.org/10.3201/eid1906.120906
Descripción
Sumario:Prion amyloidosis occurred in the heart of 1 of 3 macaques intraperitoneally inoculated with bovine spongiform encephalopathy prions. This macaque had a remarkably long duration of disease and signs of cardiac distress. Variant Creutzfeldt-Jakob disease, caused by transmission of bovine spongiform encephalopathy to humans, may manifest with cardiac symptoms from prion-amyloid cardiomyopathy.

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