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Risk factors for choroidal detachment after trabeculectomy with mitomycin C

PURPOSE: To evaluate the risk factors for choroidal detachment after trabeculectomy with mitomycin C (MMC). MATERIALS AND METHODS: We retrospectively evaluated 420 patients (420 eyes) with glaucoma who underwent trabeculectomy with MMC between June 1, 2005 and December 31, 2010 at Kumamoto Universit...

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Autores principales: Haga, Akira, Inatani, Masaru, Shobayashi, Kohei, Kojima, Sachi, Inoue, Toshihiro, Tanihara, Hidenobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713998/
https://www.ncbi.nlm.nih.gov/pubmed/23874083
http://dx.doi.org/10.2147/OPTH.S46375
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author Haga, Akira
Inatani, Masaru
Shobayashi, Kohei
Kojima, Sachi
Inoue, Toshihiro
Tanihara, Hidenobu
author_facet Haga, Akira
Inatani, Masaru
Shobayashi, Kohei
Kojima, Sachi
Inoue, Toshihiro
Tanihara, Hidenobu
author_sort Haga, Akira
collection PubMed
description PURPOSE: To evaluate the risk factors for choroidal detachment after trabeculectomy with mitomycin C (MMC). MATERIALS AND METHODS: We retrospectively evaluated 420 patients (420 eyes) with glaucoma who underwent trabeculectomy with MMC between June 1, 2005 and December 31, 2010 at Kumamoto University Hospital, Japan. Choroidal detachment after trabeculectomy was defined as a solid-appearing elevation of the retina and choroid. Logistic multivariable analysis was applied to determine the risk factors for choroidal detachment. The following factors were assessed: gender, age, subtypes of glaucoma, eye laterality, history of previous cataract surgery, preoperative intraocular pressure (IOP; mean of three Goldmann applanation readings recorded on different days), postoperative IOP (mean of seven Goldmann applanation readings recorded on 7 consecutive days after trabeculectomy), and postoperative laser suture lysis. RESULTS: Of the 420 patients, 79 (18.8%) revealed choroidal detachments. The mean period between trabeculectomy and choroidal detachment was 6.1 ± 3.6 days. The mean IOP at the time of the choroidal detachment was 5.5 ± 3.6 mmHg. Age (odds ratio [OR] = 1.028/year, P = 0.0068) and postoperative IOP (OR = 0.887/mmHg, P < 0.0001) were risk factors for choroidal detachment after trabeculectomy. The subgroup analysis for eyes with open angle glaucoma (201 patients) revealed that age (OR = 1.060/year, P = 0.0040) and postoperative IOP (OR = 0.898/mmHg, P = 0.0110) were significant risk factors for choroidal detachment after trabeculectomy with MMC. CONCLUSION: Among glaucoma patients, older age and lower postoperative IOP are risk factors for choroidal detachment after trabeculectomy with MMC. In eyes with open angle glaucoma, older age and lower postoperative IOP are risk factors for choroidal detachment after trabeculectomy with MMC.
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spelling pubmed-37139982013-07-19 Risk factors for choroidal detachment after trabeculectomy with mitomycin C Haga, Akira Inatani, Masaru Shobayashi, Kohei Kojima, Sachi Inoue, Toshihiro Tanihara, Hidenobu Clin Ophthalmol Original Research PURPOSE: To evaluate the risk factors for choroidal detachment after trabeculectomy with mitomycin C (MMC). MATERIALS AND METHODS: We retrospectively evaluated 420 patients (420 eyes) with glaucoma who underwent trabeculectomy with MMC between June 1, 2005 and December 31, 2010 at Kumamoto University Hospital, Japan. Choroidal detachment after trabeculectomy was defined as a solid-appearing elevation of the retina and choroid. Logistic multivariable analysis was applied to determine the risk factors for choroidal detachment. The following factors were assessed: gender, age, subtypes of glaucoma, eye laterality, history of previous cataract surgery, preoperative intraocular pressure (IOP; mean of three Goldmann applanation readings recorded on different days), postoperative IOP (mean of seven Goldmann applanation readings recorded on 7 consecutive days after trabeculectomy), and postoperative laser suture lysis. RESULTS: Of the 420 patients, 79 (18.8%) revealed choroidal detachments. The mean period between trabeculectomy and choroidal detachment was 6.1 ± 3.6 days. The mean IOP at the time of the choroidal detachment was 5.5 ± 3.6 mmHg. Age (odds ratio [OR] = 1.028/year, P = 0.0068) and postoperative IOP (OR = 0.887/mmHg, P < 0.0001) were risk factors for choroidal detachment after trabeculectomy. The subgroup analysis for eyes with open angle glaucoma (201 patients) revealed that age (OR = 1.060/year, P = 0.0040) and postoperative IOP (OR = 0.898/mmHg, P = 0.0110) were significant risk factors for choroidal detachment after trabeculectomy with MMC. CONCLUSION: Among glaucoma patients, older age and lower postoperative IOP are risk factors for choroidal detachment after trabeculectomy with MMC. In eyes with open angle glaucoma, older age and lower postoperative IOP are risk factors for choroidal detachment after trabeculectomy with MMC. Dove Medical Press 2013 2013-07-11 /pmc/articles/PMC3713998/ /pubmed/23874083 http://dx.doi.org/10.2147/OPTH.S46375 Text en © 2013 Haga et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Haga, Akira
Inatani, Masaru
Shobayashi, Kohei
Kojima, Sachi
Inoue, Toshihiro
Tanihara, Hidenobu
Risk factors for choroidal detachment after trabeculectomy with mitomycin C
title Risk factors for choroidal detachment after trabeculectomy with mitomycin C
title_full Risk factors for choroidal detachment after trabeculectomy with mitomycin C
title_fullStr Risk factors for choroidal detachment after trabeculectomy with mitomycin C
title_full_unstemmed Risk factors for choroidal detachment after trabeculectomy with mitomycin C
title_short Risk factors for choroidal detachment after trabeculectomy with mitomycin C
title_sort risk factors for choroidal detachment after trabeculectomy with mitomycin c
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713998/
https://www.ncbi.nlm.nih.gov/pubmed/23874083
http://dx.doi.org/10.2147/OPTH.S46375
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